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CM112

CAT: 0931-T207744-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T207744-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
CM112 is a selective degrader of protein arginine methyltransferase 1 (PRMT1), which connects a hydrophobic adamantane tag to MS023 via a 5-PEG linker. It induces the degradation of PRMT1 in various solid tumor cell lines. CM112 also targets the non-enzymatic functions of PRMT1 by reducing the stability of the orphan receptor TR3. This compound shows potential for cancer research.
Molecular Formula
C39H61N5O7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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