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T0080

CAT: 0931-T207682-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T207682-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2785323-68-2
Target
Interleukin, Apoptosis, Reactive Oxygen Species
Related Pathways
Apoptosis, Immunology/Inflammation, NF-κB, Metabolism
Bioactivity
T0080 is an FPR-1 antagonist. It reduces apoptosis (Apoptosis) and inhibits the production of reactive oxygen species (ROS) and pro-inflammatory cytokines (TNF-α and IL-1β) in plaque macrophages within ApoE−/− mouse models, thereby slowing the progression of atherosclerosis.
Smiles
O=C1C2=NNC(C=3C=C(C=CC3O)C)=C2C(C4=CC=C(C=C4)C(F)(F)F)N1C5CCOCC5
Molecular Formula
C24H22F3N3O3
Molecular Weight
457.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19250579-01T0080

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