Products for Research Use Only

AZD1134

CAT: 0931-T207317-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T207317-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
442548-99-4
Target
5-HT Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
AZD1134 is an orally active, brain-penetrant, and highly selective 5-HT1B receptor antagonist with IC50 values of 2.9 nM (human) and 0.108 nM (guinea pig) . It elevates synaptic serotonin levels in guinea pigs and holds potential for research in mental disorders such as depression and anxiety.
Smiles
O=C1C=C(OC=2C1=CC(F)=CC2N3CCN(C)CC3)C(=O)NC4=CC=C(C=C4)N5CCN(C(=O)CC)CC5
Molecular Formula
C28H32FN5O4
Molecular Weight
521.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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