Products for Research Use Only

KIF2C-IN-1

CAT: 0931-T207280-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T207280-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Kinesin
Related Pathways
Cytoskeletal Signaling
Bioactivity
KIF2C-IN-1 (Compound 7S9) is a selective and potent small molecule inhibitor of KIF2C. It stabilizes the interaction between KIF2C and microtubule proteins, preventing the depolymerization of polyglutamylated microtubules. KIF2C-IN-1 enhances the cytotoxicity of Paclitaxel in Paclitaxel-resistant triple-negative breast cancer (TNBC) cells and, when combined with Paclitaxel, significantly reduces tumor growth in mouse models.
Molecular Formula
C36H39ClN4O9S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C