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JNN-5

CAT: 0931-T207259-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T207259-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
JAK
Related Pathways
JAK/STAT signaling, Angiogenesis, Stem Cells, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors
Bioactivity
JNN-5 is an effective JAK2 selective inhibitor with an IC50 of 0.41 nM. It demonstrates strong antiproliferative activity in TNBC cell lines [MDA-MB-468, MDA-MB-213, HCC70, MDA-MB-157].
Smiles
CC1=C(C2=CN(C(C)C)N=C2)N=C(NC3=CC(CCN(C(/C=C/C(C4=CC=C(Cl)C=C4)=O)=O)C5)=C5C=C3)N=C1
Molecular Formula
C30H29ClN6O2
Molecular Weight
541.04
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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