Rhodblock 1a

• Target:

  ROCK

• Related Pathways:

  Stem Cells|||Cell Cycle/Checkpoint|||Cytoskeletal Signaling

• Bioactivity:

  Rhodblock 1a is an inhibitor of the Rho kinase signaling pathway, which disrupts the localization and function of proteins within the Rho pathway. This interference hinders the proper formation of the cleavage furrow during cell division, leading to some cells either failing to form the cleavage furrow or forming a ruptured furrow, resulting in binucleated cells. Rhodblock 1a can be utilized for investigating cell division mechanisms and holds potential for research into cardiovascular diseases and cancer.

• Smiles:

  O=C (C=1OC=CC1) N2N=C (C=3C=CC=CC3) CC2C=4C=CC=CC4

• Molecular Formula:

  C20H16N2O2

• Molecular Weight:

  316.353

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  701226-08-6