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D-G23

CAT: 0931-T206763-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206763-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1225141-73-0
Target
DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Bioactivity
D-G23 is a selective RAD52 inhibitor. It disrupts RAD52-mediated DNA repair pathways and suppresses the growth of cancer cells deficient in BRCA1 and BRCA2. D-G23 shows promise for research into homologous recombination-related cancers caused by BRCA1/2 mutations, such as hereditary breast and ovarian cancers.
Smiles
OCCCNC=1N=C(N=C2C=CC=CC21)NC3=CC(OC)=CC=C3OC
Molecular Formula
C19H22N4O3
Molecular Weight
354.403
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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