CHD-1

CAT: 0931-T206731-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T206731-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

3041166-70-2

Target

Apoptosis, Mitophagy

Related Pathways

Autophagy, Apoptosis

Bioactivity

CHD-1 is a hypoxia-activated antitumor prodrug. It disrupts the mitochondrial morphology and membrane potential of hypoxic tumor cells, leading to excessive mitophagy and inducing apoptosis. In vitro, CHD-1 inhibits the growth of hypoxic tumor cells, while in vivo, it suppresses the growth of HeLa xenograft tumors.

Smiles

C(/C=C/C1=CC(N(=O)=O)=CC=C1)(=O)C2=CC(F)=C(OC)C=C2

Molecular Formula

C16H12FNO4

Molecular Weight

301.269

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-170565	CHD-1
558461-01	Chd
BA5845-5	CHD-5
558464-01	Chd (HRP)
MBS7051853-01	chd Antibody
558463-01	Chd (FITC)
558462-01	Chd (Biotin)
GTR17881649-01	Chd Antibody (Biotin)
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CHD-1

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