CHD-1

• CAS Number :

  3041166-70-2

• Target :

  Apoptosis|||Mitophagy

• Related Pathways :

  Autophagy|||Apoptosis

• Bioactivity :

  CHD-1 is a hypoxia-activated antitumor prodrug. It disrupts the mitochondrial morphology and membrane potential of hypoxic tumor cells, leading to excessive mitophagy and inducing apoptosis. In vitro, CHD-1 inhibits the growth of hypoxic tumor cells, while in vivo, it suppresses the growth of HeLa xenograft tumors.

• Smiles :

  C(/C=C/C1=CC(N(=O)=O)=CC=C1)(=O)C2=CC(F)=C(OC)C=C2

• Molecular Formula :

  C16H12FNO4

• Molecular Weight :

  301.269

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C