Insecticidal agent 21

• Target:

  Others|||Sodium Channel|||Cholinesterase (ChE) |||AChR|||GABA Receptor

• Related Pathways:

  Membrane transporter/Ion channel|||Neuroscience|||Others

• Bioactivity:

  Insecticidal agent 21 (Compound 6) is an insecticide targeting Culex pipiens larvae with an LC50 of 0.4 ?g/mL. It achieves multi-target neurotoxicity by inhibiting acetylcholinesterase (AChE) and simultaneously targeting other neural receptors, including nicotinic acetylcholine receptors (nAChR), voltage-gated sodium channels (VGSC), and ?-aminobutyric acid receptors (GABAAR) . Insecticidal agent 21 shows potent insecticidal activity and can be utilized in the development of new insecticides to combat mosquito resistance to conventional agents.

• Smiles:

  O=C1C(=CC=2C=C3C=CC=4C=CC=CC4C3=NC2Cl)C=C(C=5C=CC(=CC5)C)N1NC(=O)CCCCCCCCCCC

• Molecular Formula:

  C37H40ClN3O2

• Molecular Weight:

  594.185

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3082443-45-3