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UNC9426

CAT: 0931-T206681-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T206681-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3051784-94-9
Target
Platelet aggregation, TAM Receptor
Related Pathways
Others, Tyrosine Kinase/Adaptors
Purity
0.98051
Bioactivity
UNC9426 is an orally active, potent and selective TYRO3 inhibitor with an IC50 of 2.1 nM. It reduces platelet aggregation without prolonging bleeding time and blocks TYRO3-dependent functions in tumour cells and macrophages, making it suitable for studying thrombosis and platelet aggregation.
Smiles
N(C=1N=C2C(C(=CN2[C@H]3CC[C@H](O)CC3)C4=CC=C(CN5CCN(C)CC5)C=C4)=CN1)C6=CC(C(F)(F)F)=CC(C(F)(F)F)=C6
Molecular Formula
C32H34F6N6O
Molecular Weight
632.642
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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