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A-86929

CAT: 0931-T206564-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206564-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
171961-95-8
Target
Dopamine Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
A-86929 is a potent and selective dopamine D1 receptor agonist with a pKi of 7.3. It significantly induces rotational behavior in a 6-OHDA-induced unilateral nigral lesion rat model and improves motor function in an MPTP-induced Parkinson's disease marmoset model. Furthermore, A-86929 shows potential value in reducing cocaine-induced craving behavior in rats and reversing Haloperidol-induced cognitive deficits in rhesus monkeys. The compound is useful for researching neurological disorders.
Smiles
C(CC)C1=CC=2[C@@]3(C=4C(CC[C@]3(NCC2S1)[H])=CC(O)=C(O)C4)[H]
Molecular Formula
C18H21NO2S
Molecular Weight
315.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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CatalogName
HY-171472A-86929

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