Products for Research Use Only
RegisterLogin

Balomenib

CAT: 0931-T206488-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T206488-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2939850-17-4
Target
Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Bioactivity
Balomenib is an inhibitor of the menin-MLL interaction, effectively blocking the men1-MLL4-43 interaction with an IC50 of less than 0.075 μM. It inhibits cell growth in MV4-11 (CC50 < 0.1 μM), MOLM-13 (CC50 0.1~0.5 μM), and HEK293 (CC50 < 2 μM) cells. Balomenib also exhibits antitumor activity.
Smiles
C(N1CCC2(CN(C2)C=3C4=C(C=CC(CC(F)(F)F)=C4)N=CN3)CC1)C=5C(C)=C6C(=CC5)N(C[C@@H]7CNC(=O)CO7)C(C#N)=C6
Molecular Formula
C33H34F3N7O2
Molecular Weight
617.664
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
RG-E141623-01Balomenib

Popular Products