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DA-1241

CAT: 0931-T206401-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206401-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1914136-10-9
Target
GPCR
Related Pathways
GPCR/G Protein, Endocrinology/Hormones
Bioactivity
DA-1241 is a GPR119 agonist. By activating GPR119, it downregulates NFκB signaling, thereby inhibiting macrophage differentiation. Whether used alone or in combination with DPP4 inhibitors, DA-1241 can alleviate liver inflammation and restore the expression of liver genes linked to inflammation. It is applicable in the research of metabolic dysfunction-associated steatohepatitis (MASH) .
Smiles
FC1=CC(OCCCC2CCN(C3=NC=C(C=N3)CC)CC2)=CC(F)=C1C4=NOC(=N4)C(C)C
Molecular Formula
C25H31F2N5O2
Molecular Weight
471.543
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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