DA-1241

• Target:

  GPCR

• Related Pathways:

  GPCR/G Protein|||Endocrinology/Hormones

• Bioactivity:

  DA-1241 is a GPR119 agonist. By activating GPR119, it downregulates NF?B signaling, thereby inhibiting macrophage differentiation. Whether used alone or in combination with DPP4 inhibitors, DA-1241 can alleviate liver inflammation and restore the expression of liver genes linked to inflammation. It is applicable in the research of metabolic dysfunction-associated steatohepatitis (MASH) .

• Smiles:

  FC1=CC(OCCCC2CCN(C3=NC=C(C=N3)CC)CC2)=CC(F)=C1C4=NOC(=N4)C(C)C

• Molecular Formula:

  C25H31F2N5O2

• Molecular Weight:

  471.543

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1914136-10-9