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Epaldeudomide

CAT: 0931-T206325-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206325-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1918159-31-5
Target
TNF
Related Pathways
Apoptosis
Bioactivity
Epaldeudomide (Compound A406) is an inhibitor of TNF-α, showing an inhibition rate of over 50% at 100 nM. It effectively suppresses the proliferation of cancer cells MM.1S (IC50 < 300 nM), WSU-DLCL-2 (IC50 < 100 nM), and Rec-1 (IC50 < 100 nM) . Epaldeudomide exhibits antitumor activity.
Smiles
O(CC1=C(F)C=C(CN2CCOCC2)C=C1)C3=C4C(C(=O)N(C4)[C@@]5(C(=O)NC(=O)CC5)[2H])=CC=C3
Molecular Formula
C25H26FN3O5
Molecular Weight
468.496
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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