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TREK inhibitor-3

CAT: 0931-T206065-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206065-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3023854-95-4
Target
Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
TREK inhibitor-3 (Cpd8l) is a selective inhibitor of TREK-1 that can cross the blood-brain barrier, with an IC50 of 0.81 μM. It offers neuroprotective effects by significantly reducing cortical neuron death induced by oxygen-glucose deprivation/reoxygenation (OGD/R) and alleviating brain injury in middle cerebral artery occlusion/reperfusion (MCAO/R) model mice. TREK inhibitor-3 is utilized in ischemic stroke research.
Smiles
O=C1OC(C2=CC=C(C=C12)C3CCNCC3)CC=4C=CC=CC4C
Molecular Formula
C21H23NO2
Molecular Weight
321.413
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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