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FFA2 agonist-1

CAT: 0931-T205726-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205726-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1312799-06-6
Target
GPCR
Related Pathways
GPCR/G Protein, Endocrinology/Hormones
Bioactivity
FFA2 agonist-1 (Compound 4) is an agonist of the free fatty acid receptor 2 (FFA2/GPR43) with an EC50 of 81 nM. It demonstrates activity in β-arrestin-2 recruitment and cAMP inhibition assays, with EC50 values of 1.2 μM and 0.53 μM, respectively. FFA2 agonist-1 can induce the mucosal response of appetite-regulating peptide YY (PYY), inhibit fat accumulation, and affect intestinal function and food intake, making it useful for obesity research.
Smiles
C(=O)(N1[C@H](CC[C@H]1C(O)=O)C2=C(Cl)C=CC=C2)C3=CC=C(C=C3)C4=C(OC)C=CC=C4
Molecular Formula
C25H22ClNO4
Molecular Weight
435.899
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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