FFA2 agonist-1

• CAS Number :

  1312799-06-6

• Target :

  GPCR

• Related Pathways :

  GPCR/G Protein|||Endocrinology/Hormones

• Bioactivity :

  FFA2 agonist-1 (Compound 4) is an agonist of the free fatty acid receptor 2 (FFA2/GPR43) with an EC50 of 81 nM. It demonstrates activity in ?-arrestin-2 recruitment and cAMP inhibition assays, with EC50 values of 1.2 ?M and 0.53 ?M, respectively. FFA2 agonist-1 can induce the mucosal response of appetite-regulating peptide YY (PYY), inhibit fat accumulation, and affect intestinal function and food intake, making it useful for obesity research.

• Smiles :

  C(=O)(N1[C@H](CC[C@H]1C(O)=O)C2=C(Cl)C=CC=C2)C3=CC=C(C=C3)C4=C(OC)C=CC=C4

• Molecular Formula :

  C25H22ClNO4

• Molecular Weight :

  435.899

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C