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SDUY816

CAT: 0931-T205619-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205619-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Aminopeptidase, Neprilysin
Related Pathways
Metabolism
Bioactivity
SDUY816 is an orally active dual APN/NEP inhibitor, with IC50 values of 0.68 μM for APN and 6.9 μM for NEP. It exhibits analgesic properties and demonstrates good safety and pharmacokinetic profiles, having an oral bioavailability of 27% and a half-life of 4.02 hours in rats (oral, 10 mg/kg) . SDUY816 is applicable for research in the field of neuropathic pain disorders.
Molecular Formula
C18H16IN3O3
Molecular Weight
449.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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