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HZS60

CAT: 0931-T205600-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205600-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3027529-88-7
Target
TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
HZS60 is a brain-penetrant NMDAR/TRPM4 inhibitor that shows promise in ameliorating cerebral ischemia. It provides significant neuroprotection against ischemic injury in primary neurons caused by NMDA and oxygen-glucose deprivation/reoxygenation. HZS60 demonstrates favorable pharmacokinetic properties and can inhibit cerebral ischemia-reperfusion injury, positioning it as a potential inhibitor for ischemic stroke.
Smiles
N#CC1=CC=C(F)C(=C1F)C(N(CC)CCN)C
Molecular Formula
C13H17F2N3
Molecular Weight
253.291
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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