BRD6257

CAT: 0931-T205561-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T205561-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Phosphatase|||MDM-2/p53
Related Pathways
Apoptosis|||Metabolism
Bioactivity
BRD6257 is an orally active inhibitor of protein phosphatase 1D (proteinphosphatase, Mg2+/Mn2+ dependent 1D, PPM1D) with an IC50 of 5 nM. It activates the p53 signaling pathway (EC50 of 51 nM), enhances p21 expression, and inhibits the proliferation of cancer cells MOLM13 (IC50 = 2.8 ?M) . BRD6257 demonstrates good metabolic stability in human and rat liver microsomes.
Molecular Formula
C24H22F4N6O3S
Molecular Weight
550.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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CatalogName
HY-173084BRD6257

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