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SRSF1-IN-1

CAT: 0931-T205515-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205515-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Serine/threonin kinase
Related Pathways
Cell Cycle/Checkpoint, Metabolism
Bioactivity
SRSF1-IN-1 (STP2) is an inhibitor of SRSF1 that modulates the splicing of Bcl-x precursor mRNA by downregulating SRSF1 expression. It exhibits antitumor activity in vitro and in vivo, with IC50 values ranging from 0.33 to 6.93 μM against cancer cells such as HepG2 and MCF7. In mice, SRSF1-IN-1 demonstrates a high safety profile, as intraperitoneal administration of 1 g/kg does not lead to mortality or pathological damage. SRSF1-IN-1 holds potential for research in the field of antitumor therapy [1].
Molecular Formula
C20H24O5S
Molecular Weight
376.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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