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LNK01004

CAT: 0931-T205387-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205387-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2445500-24-1
Target
JAK, STAT
Related Pathways
JAK/STAT signaling, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Stem Cells, Angiogenesis
Bioactivity
LNK01004 is a JAK inhibitor that exhibits potent inhibitory effects on JAK1 (IC50: 10 nM), JAK2 (IC50: <0.51 nM), and TYK2 (IC50: 1.0 nM) . It can concurrently inhibit multiple cytokine-induced p-STAT signaling pathways and is applicable for research on diseases such as atopic dermatitis.
Smiles
N#CCNC(=O)C=1C=CC(=CC1)C2=NC(=NC=C2C)NC=3C=NN(C3)C4CC(OC(C)(C)C4)(C)C
Molecular Formula
C26H31N7O2
Molecular Weight
473.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-171242LNK01004

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