PRC1-IN-1

• CAS Number :

  2396639-29-3

• Target :

  E1/E2/E3 Enzyme

• Related Pathways :

  Ubiquitination

• Bioactivity :

  PRC1-IN-1 (compound RB-4) is an inhibitor of the polycomb repressive complex 1 (PRC1) with an IC50 of 2.3 ?M. It targets RING1B-BMI1, RING1A-BMI1, and RING1B-PCGF1, exhibiting IC50 values of 2.8 ?M, 2.6 ?M, and 1.8 ?M, respectively.

• Smiles :

  O=C(O)C=1NC(C=2C=C(F)C=C3NC=CC32)=C(C1C=4C(Cl)=CC=C5NC=CC54)C(C)C

• Molecular Formula :

  C24H19ClFN3O2

• Molecular Weight :

  435.878

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C