TREX1-IN-3

CAT: 0931-MF-0113665-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0113665-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2588445-13-8
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Bioactivity
TREX1-IN-3 (Compound 95) is an inhibitor of TREX1 and TREX2, with an IC50 of less than 0.1 ?M for TREX1 and less than 1 ?M for TREX2, as well as an EC50 of less than 1 ?M for HCT116 cells. It is applicable for research in the field of cancer.
Smiles
[C@@H](N(C)C1=NC(C(NC=2C=NOC2)=O)=C(O)C(=O)N1C)(C3=CC(C#N)=CC=C3)C4=C(Cl)C=CC=C4
Molecular Formula
C24H19ClN6O4
Molecular Weight
490.898
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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