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DXR-IN-4

CAT: 0931-T205183-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205183-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Parasite
Related Pathways
Microbiology/Virology
Bioactivity
DXR-IN-4 (Compound 12a) is an inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) . It effectively inhibits DXR in Plasmodium falciparum, Escherichia coli, and Mycobacterium tuberculosis, with IC50 values for PfDXR, EcDXR, and MtDXR at 18, 4.9, and 89 nM, respectively. Additionally, DXR-IN-4 demonstrates antimalarial activity against Plasmodium falciparum strains 3D7 and Dd2, with IC50 values of 11 μM and 12 μM.
Molecular Formula
C16H26NO6PS
Molecular Weight
391.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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