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Quorum sensing-IN-9

CAT: 0931-T205120-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205120-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3063543-24-5
Target
Antibacterial
Related Pathways
Microbiology/Virology
Bioactivity
Quorum sensing-IN-9 (Compound 7d) inhibits quorum sensing in Pseudomonas aeruginosa by binding to the PqsR protein. It suppresses the expression of quorum sensing system-related genes lasB, rhlA, and pqsA, thereby preventing the production of virulence factors elastase, pyocyanin, and rhamnolipid. Quorum sensing-IN-9 disrupts the motility of P. aeruginosa, inhibits biofilm formation, and reduces the bacterium's virulence and pathogenicity. Additionally, it exhibits anti-infective activity in the Galleria mellonella larval model.
Smiles
OC1=CC=C(SSCC=C)C=C1
Molecular Formula
C9H10OS2
Molecular Weight
198.305
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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