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CZY43

CAT: 0931-T204925-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204925-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
EGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
Bioactivity
CZY43 is an HER3 degrader that effectively induces degradation of HER3 in breast cancer SKBR3 cells in a dose- and time-dependent manner. It efficiently inhibits HER3-dependent signaling and cancer cell growth, outperforming Bosutinib.
Smiles
COC1=C(C=C2C(=C1)C(=C(C=N2)C#N)NC3=CC(=C(C=C3Cl)Cl)OC)OCCCN4CCC5(CC4)CCN(CC5)CCC67CC8CC(C6)CC(C8)C7
Molecular Formula
C42H53Cl2N5O3
Molecular Weight
746.808
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19249728-01CZY43

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