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AB8939

CAT: 0931-T204846-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204846-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1974336-09-8
Target
Microtubule Associated, Apoptosis
Related Pathways
Apoptosis, Cytoskeletal Signaling
Bioactivity
AB8939 is a potent small-molecule inhibitor of microtubule/tubulin polymerization, exhibiting antitumor activity (with tumor cell proliferation inhibition IC50≤10 nM) . It effectively circumvents resistance mechanisms mediated by P-glycoprotein and myeloperoxidase. AB8939 can induce G2/M phase cell cycle arrest and apoptosis.
Smiles
O=C1NCCN1C=2C=CC(=CC2)C=3OC(=NC3)NC4=CC(=CC=C4C)COCC
Molecular Formula
C22H24N4O3
Molecular Weight
392.451
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19249814-01AB8939

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