PET-cGMP

• Target:

  PKA

• Related Pathways:

  Tyrosine Kinase/Adaptors

• Bioactivity:

  PET-cGMP is an analogue of cyclic guanosine monophosphate and functions as a potent, selective agonist for PKGI. It exhibits an EC50 of 3.8 nM for PKGI? and 193 nM for PKGII.

• Smiles:

  O=C1C2=C(N(C=N2)[C@@H]3O[C@]4([C@]([C@H]3O)(OP(=O)(O)OC4)[H])[H])NC=5N1C=C(N5)C6=CC=CC=C6

• Molecular Formula:

  C18H16N5O7P

• Molecular Weight:

  445.323

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  78080-27-0