Antioxidant agent-20

• Target:

  Reactive Oxygen Species|||NF-?B|||Apoptosis|||ROS|||Nrf2

• Related Pathways:

  Metabolism|||Immunology/Inflammation|||NF-?B|||Apoptosis

• Bioactivity:

  Antioxidant agent-20 (Compound 3d) exhibits potent anti-inflammatory and antioxidant activities. It reduces reactive oxygen species (ROS) and apoptosis in a dose-dependent manner. Antioxidant agent-20 demonstrates photoprotective effects on UVB-exposed human skin keratinocytes (HaCaT) (IC50=5.13 µM) by activating Nrf2/HO-1 signaling and inhibiting the NF-?B pathway.

• Smiles:

  CC1=C (C2=C (CCC (O2) (C) C (=O) OC3CCC3) C (=C1O) C) C

• Molecular Formula:

  C18H24O4

• Molecular Weight:

  304.381

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C