Products for Research Use Only
RegisterLogin

DNA ligase-IN-2

CAT: 0931-T204415-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T204415-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
635681-64-0
Target
DNA/RNA Synthesis, Antibacterial
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Microbiology/Virology
Bioactivity
DNA ligase-IN-2 (compound 2) acts as a potent LigA inhibitor, effectively hindering the DNA-independent spontaneous adenylation activity of full-length LigA and the truncated enzyme LigA:AD with an IC50 of 29 nM. It also significantly suppresses the in vitro growth of Staphylococcus aureus, showing MIC values of 1 μg/mL for S. aureus ATCC 29213 and S. aureus ATCC 700699, while the MIC for Escherichia coli (E. coli) ATCC 25922 is >64 μg/mL.
Smiles
O=C(N)C1=CC=2C(=O)C3=CC(F)=CC=C3OC2N=C1N
Molecular Formula
C13H8FN3O3
Molecular Weight
273.219
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T203170-01DNA ligase-IN-1
TRP-00559-01E. coli DNA ligase
TMAB-05210-01Anti-DNA Ligase III Polyclonal Antibody
TMAB-05209-01Anti-DNA Ligase 1 Antibody (4I673)
TMAB-05208-01Anti-DNA Ligase 1 Polyclonal Antibody
TMAB-05212-01Anti-DNA Ligase IV Antibody (5M82)
TMAB-05211-01Anti-DNA Ligase IV Polyclonal Antibody
TMPH-00425-01DNA ligase Protein, Colwellia psychrerythraea, Recombinant (His)
TMPH-00475-01DNA ligase Protein, Desulfotalea psychrophila, Recombinant (His)
T209118-01E3 Ligase Ligand-linker Conjugate 2

Alternative Products

CatalogName
M0239ST4 RNA Ligase 2 (dsRNA Ligase)
GTR19250253-01DNA ligase-IN-2
HBP001104T4 RNA ligase 2
MBS3604724-01E3 Ligase Ligand 2
M1220-100T4 RNA Ligase 2 (Truncated)
RK20505-01T4 RNA Ligase 2, truncated
BAL926T4 RNA Ligase 2 (dsRNA Ligase), 1 pack = 150 U
BAL927T4 RNA Ligase 2 (dsRNA Ligase), 1 pack = 750 U
353040SMURF 2 (E3 Ubiquitin-Protein Ligase SMURF2, SMAD Specific E3 Ubiquitin Protein Ligase 2)
R0637MT4 RNA Ligase 2, truncated KQ

Popular Products