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ERBB agonist-1

CAT: 0931-T204401-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T204401-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
930856-19-2
Target
Akt, EGFR, ERK
Related Pathways
PI3K/Akt/mTOR signaling, Angiogenesis, JAK/STAT signaling, MAPK, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling
Purity
0.999
Bioactivity
ERBB agonist-1 (Compound EF-1) is an ERBB4 agonist (EC50=10.5 μM) that induces ERBB4 receptor dimerization and phosphorylation of Akt and ERK1/2. It exhibits cardioprotective effects in mouse models and prevents myocardial fibrosis.
Smiles
O=C1C=2C=CC=CC2N=C(SC(C(=O)NC3CC3)C=4C=CC=CC4)N1C5CCCC5
Molecular Formula
C24H25N3O2S
Molecular Weight
419.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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