Products for Research Use Only

UCB9386

CAT: 0931-T204179-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204179-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
AMPK, JAK
Related Pathways
Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Angiogenesis, PI3K/Akt/mTOR signaling, JAK/STAT signaling, Stem Cells
Bioactivity
UCB9386 is a brain-penetrant and selective inhibitor of Nuak1, with a pIC50 of 10.1. It also inhibits Nuak2 and Kak2, showing approximately 50% inhibition at 10 nM.
Smiles
C[C@H](C1=CC=CC=C1)N2C3=CC(=NC=C3N=C(C2=O)N4CC5(C4)CN(C5)C)C6=CN=C7N6N=CC=C7
Molecular Formula
C27H26N8O
Molecular Weight
478.548
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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