Products for Research Use Only

JRD-SIK1/2i-4

CAT: 0931-T204011-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204011-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2810810-00-3
Target
Interleukin, SIK, TNF
Related Pathways
Apoptosis, PI3K/Akt/mTOR signaling, Immunology/Inflammation
Bioactivity
JRD-SIK1/2i-4 is a SIK1/2 inhibitor that induces nuclear translocation of CRTC3 at low micromolar concentrations. It is expected to saturate SIK1 and SIK2, but not SIK3.
Smiles
N#CC=1N=CC(OC2CN(C)C2)=C(C1)C=3C=CN4N=C(C=C4C3)NC(=O)C5CC5
Molecular Formula
C21H20N6O2
Molecular Weight
388.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C