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BTX6654

CAT: 0931-T203787-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203787-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Kras, PROTACs, Ras, ERK
Related Pathways
PROTAC, MAPK
Bioactivity
BTX-6654 is a cereblon-based bifunctional SOS1 PROTAC degrader. This compound exhibits antiproliferative activity against cells with various KRAS mutations by reducing the expression of downstream signaling markers pERK and pS6.
Smiles
FC(F)(F)C1=C(C)C([C@@H](C)NC2=NN=C(C)C3=CC=C(N4CCN(C(C5CCN(C(CCN6CCC(C7=CC(CN(C8CCC(NC8=O)=O)C9=O)=C9C=C7F)CC6)=O)CC5)=O)CC4)C=C32)=CC=C1
Molecular Formula
C50H57F4N9O5
Molecular Weight
940.04
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19240860-01BTX6654

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