Perfluorotetradecanoic acid

• CAS Number :

  376-06-7

• Target :

  PPAR|||Apoptosis

• Related Pathways :

  Apoptosis|||Metabolism|||DNA Damage/DNA Repair

• Bioactivity :

  Perfluorotetradecanoic acid (PFTeDA) is a PPAR? antagonist. It binds to the ligand-binding domain of human PPAR?, with an IC50 of 22.8 ?M and a Kd of 157.8 ?M. Perfluorotetradecanoic acid inhibits Leydig cell function by inducing oxidative stress and apoptosis (Apoptosis) . Although it stimulates corticosterone biosynthesis, it inhibits aldosterone production.

• Smiles :

  O=C(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

• Molecular Formula :

  C14HF27O2

• Molecular Weight :

  714.11

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C