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Cladophorol A

CAT: 0931-T203535-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203535-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
146776-30-9
Target
STING, cGAS
Related Pathways
Immunology/Inflammation
Bioactivity
Cladophorol A is a cGAS inhibitor that obstructs its activity by binding to the conserved adenosine nucleotide binding site of cGAS. It effectively suppresses the overactivation of the cGAS-STING pathway at non-cytotoxic concentrations, with an IC50 of 370 nM. Cladophorol A holds potential for research into inflammatory diseases linked to the overactivation of the cGAS-STING pathway.
Smiles
O=C1OC2=CC(O)=C(O)C=C2C=3C=C(O)C(O)=CC13
Molecular Formula
C13H8O6
Molecular Weight
260.2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19241110-01Cladophorol A

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