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HCA I-IN-4

CAT: 0931-T203530-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203530-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3054159-56-4
Target
Cholinesterase (ChE), Carbonic Anhydrase
Related Pathways
Neuroscience, Metabolism
Bioactivity
HCA I-IN-4 (Compound 14) is an inhibitor of carbonic anhydrase and cholinesterase, effectively inhibiting hCA I, hCA II, AChE, and BChE with Ki values of 29.94 nM, 17.72 nM, 21.21 nM, and 7.65 nM, respectively. It also demonstrates cytotoxicity in BT-549 cells, with an IC50 of 16.59 μM.
Smiles
N=1C=CC=C(C1)N2N=NC(=C2)CN3C=4C=CC=CC4C=CC=5C=CC=CC53
Molecular Formula
C22H17N5
Molecular Weight
351.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C