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Kanglexin

CAT: 0931-T203479-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203479-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2228847-12-7
Target
FGFR, Pyroptosis, AMPK, NOD-like Receptor (NLR), ERK
Related Pathways
PI3K/Akt/mTOR signaling, Tyrosine Kinase/Adaptors, Immunology/Inflammation, Apoptosis, MAPK, Angiogenesis, Chromatin/Epigenetic
Bioactivity
Kanglexin is an orally active novel anthraquinone compound. It inhibits NLRP3 inflammasome activation and pyroptosis, offering cardioprotective benefits. By stimulating the FGFR1/ERK signaling pathway, Kanglexin promotes angiogenesis and accelerates wound healing in diabetes. Additionally, it has lipid-lowering effects and inhibits vascular smooth muscle cell dedifferentiation, making it a potential compound for studying hyperlipidemia, fatty liver, and atherosclerosis.
Smiles
O=C1C=2C=C(OC(=O)CCC(=O)OCC)C=C(O)C2C(=O)C3=C(O)C=C(C=C13)C
Molecular Formula
C21H18O8
Molecular Weight
398.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-164853-01Kanglexin

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