Products for Research Use Only

NEK7-IN-1

CAT: 0931-T203437-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203437-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2738569-12-3
Target
MAPK, Others
Related Pathways
Others, MAPK
Bioactivity
NEK7-IN-1 (Compound I-15) is an inhibitor of NIMA-related kinase 7 (NEK7) with an IC50 of less than 100 nM. It also effectively inhibits the release of IL-1β, exhibiting an IC50 of less than 50 nM.
Smiles
O=C(NC1=CC=C(C(=C1)C(F)(F)F)CN2CCN(C)CC2)NC=3C=CC(=CC3F)C4=CN(C=5N=CN=C(N)C45)CC(O)(C)C
Molecular Formula
C30H34F4N8O2
Molecular Weight
614.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C