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BGC0222

CAT: 0931-T203374-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203374-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Integrin
Related Pathways
Cytoskeletal Signaling
Bioactivity
BGC0222 is a novel Irinotecan prodrug. As a PEG-cRGD conjugated derivative of Irinotecan, BGC0222 enables the slow and steady release of Irinotecan. It binds to the αVβ3 target with an IC50 of 4.25 μM and has an IC50 of 58.7 μM for αVβ5. BGC0222 can induce angiogenesis and demonstrates significant antitumor activity in various tumors.
Molecular Formula
C1241H2276N64O552
Molecular Weight
26927.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-P10783BGC0222

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