DTS-201 sodium

CAT: 0931-MF-0112307-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0112307-01Size:10 mg
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CAS Number
372491-73-1
Target
Aminopeptidase
Related Pathways
Metabolism
Bioactivity
DTS-201 sodium (CPI-0004Na) is a peptide prodrug of Doxorubicin. It contains a tetrapeptide segment that is hydrolyzed by endopeptidases in the tumor microenvironment to produce metabolites, which are then converted into active Doxorubicin upon cellular entry. DTS-201 has demonstrated antitumor efficacy in xenograft models of prostate, breast, and lung cancers.
Smiles
OC1=C2C(C(C3=C(OC)C=CC=C3C2=O)=O)=C(O)C([C@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC(C)C)NC(CCNC(CCC([O-])=O)=O)=O)=O)=O)=O)=C1C[C@](O)(C4)C(CO)=O.[Na+]
Molecular Formula
C49H64N5NaO18
Molecular Weight
1034.05
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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