DTS-201 sodium

• Target :

  Aminopeptidase

• Related Pathways :

  Metabolism

• Bioactivity :

  DTS-201 sodium (CPI-0004Na) is a peptide prodrug of Doxorubicin. It contains a tetrapeptide segment that is hydrolyzed by endopeptidases in the tumor microenvironment to produce metabolites, which are then converted into active Doxorubicin upon cellular entry. DTS-201 has demonstrated antitumor efficacy in xenograft models of prostate, breast, and lung cancers.

• Smiles :

  OC1=C2C(C(C3=C(OC)C=CC=C3C2=O)=O)=C(O)C([C@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC(C)C)NC(CCNC(CCC([O-])=O)=O)=O)=O)=O)=O)=C1C[C@](O)(C4)C(CO)=O.[Na+]

• Molecular Formula :

  C49H64N5NaO18

• Molecular Weight :

  1034.05

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  372491-73-1