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Ap4dT

CAT: 0931-T203116-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203116-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1146545-74-5
Target
DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Bioactivity
Ap4dT serves as an inhibitor of human adenylate kinase isozyme 1 (hAK1), effectively suppressing the synthesis of ATP and ADP, with IC50 values of 42 μM and 38 μM, respectively.
Smiles
O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OP(OP(OC[C@H]2O[C@@H](N3C(NC(C(C)=C3)=O)=O)C[C@@H]2O)([O-])=O)([O-])=O)([O-])=O)([O-])=O)N4C5=NC=NC(N)=C5N=C4.[NH4+].[NH4+].[NH4+].[NH4+]
Molecular Formula
C20H41N11O20P4
Molecular Weight
879.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C