Burixafor

• Bioactivity :

  Burixafor (also known as TG-0054) is an orally available inhibitor of the CXC chemokine receptor 4 (CXCR4) with receptor binding and hematopoietic stem cell mobilization activities. By binding to the CXCR4 chemokine receptor, Burixafor blocks the binding and subsequent activation of stromal cell-derived factor-1 (SDF-1 or CXCL12) with the CXCR4 receptor, potentially facilitating the mobilization of hematopoietic stem and progenitor cells from the bone marrow into the bloodstream. Note: Elemental analysis shows that this compound is a salt containing 3 HBr and 3 water molecules.

• Smiles :

  N(C[C@@H]1CC[C@@H](CNCCCNC2CCCCC2)CC1)C=3N=C(C=C(N)N3)N4CCN(CCP(=O)(O)O)CC4

• Molecular Formula :

  C27H51N8O3P

• Molecular Weight :

  566.72

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1191448-17-5