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Burixafor

CAT: 0931-T202297-01Size: 10 mgDry Ice: NoHazardous: No
CAT#: T202297-01Size: 10 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1191448-17-5
Bioactivity
Burixafor (also known as TG-0054) is an orally available inhibitor of the CXC chemokine receptor 4 (CXCR4) with receptor binding and hematopoietic stem cell mobilization activities. By binding to the CXCR4 chemokine receptor, Burixafor blocks the binding and subsequent activation of stromal cell-derived factor-1 (SDF-1 or CXCL12) with the CXCR4 receptor, potentially facilitating the mobilization of hematopoietic stem and progenitor cells from the bone marrow into the bloodstream. Note: Elemental analysis shows that this compound is a salt containing 3 HBr and 3 water molecules.
Smiles
N(C[C@@H]1CC[C@@H](CNCCCNC2CCCCC2)CC1)C=3N=C(C=C(N)N3)N4CCN(CCP(=O)(O)O)CC4
Molecular Formula
C27H51N8O3P
Molecular Weight
566.72
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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206522Burixafor HBr
MBS5752837Burixafor hydrobromide
HY-19867A-01Burixafor (hydrobromide)

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