Products for Research Use Only
RegisterLogin

Bexagliflozin diproline

CAT: 0931-T202270-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T202270-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1118567-48-8
Bioactivity
Bexagliflozin (also known as EGT1442) is a potent and selective SGLT2 inhibitor that effectively reduces blood glucose and HbA (1c) levels in db/db mice while increasing the survival time of stroke-prone rats. The IC (50) values of EGT1442 for human SGLT1 and SGLT2 are 5.6 μM and 2 nM, respectively. In studies involving normal rats and dogs, EGT1442 induces saturated urinary glucose excretion with ED (50) values of 0.38 mg/kg and 0.09 mg/kg, respectively. Additionally, EGT1442 exhibits favorable properties in both in vivo and in vitro studies, indicating its potential positive impact on the management of type 2 diabetes.
Smiles
OC([C@@H]1CCCN1)=O.O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O)CO)C3=CC(CC4=CC=C(C=C4)OCCOC5CC5)=C(C=C3)Cl.OC([C@@H]6CCCN6)=O
Molecular Formula
C34H47ClN2O11
Molecular Weight
695.2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T7217-01Bexagliflozin
T25340-01Diprotin A
T11049Diprotin A TFA
T25341-01Diprotin B

Alternative Products

CatalogName
TRC-B336785-250MGBexagliflozin
CS-O-36864Bexagliflozin D2
E0141-5mgBexagliflozin (EGT1442)
TRC-O965620-100MGOxo-Bexagliflozin
TRC-D965830-25MGDescyclopropyl Bexagliflozin
MBS131294Bexagliflozin?EGT1442
TRC-B965621-1MGBexagliflozin Ethylene-D4
TRC-H965630-50MG(S)-Hydroxy-Bexagliflozin
TRC-D965840-10MGDescyclopropyl Bexagliflozin Carboxylic Acid
TRC-H965650-100MGHydroxy-Bexagliflozin (Mixture of Diastereomers)

Popular Products