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ZNL0325

CAT: 0931-T202202-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T202202-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Bioactivity
ZNL0325 is a covalent probe based on pyrazolo[1,2-a]pyrimidine that demonstrates an alternative binding mode for kinases, where the C3 position is reversed facing the ribose-binding pocket. ZNL0325 and its analogs feature an acrylamide side chain at the C3 position, capable of forming covalent bonds with various kinases possessing cysteine at the αD-1 position, including BTK, EGFR, BLK, and JAK3.
Smiles
CC(C)(C)N1C2=NC=NC(N)=C2C(OC3CN(C(C=C)=O)C3)=N1
Molecular Formula
C15H20N6O2
Molecular Weight
316.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-163267ZNL0325

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