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CAIMP

CAT: 0931-T202010-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T202010-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1507367-51-2
Target
NF-κB, IFNAR
Related Pathways
Immunology/Inflammation, NF-κB
Bioactivity
CAIMP acts as a STING agonist and has been shown to more effectively activate STING-dependent IRF and NF-κB signaling pathways in mammalian cells in vitro when compared to standard murine (DMXAA) and human (2',3'-cGAMP) STING agonists. In ex vivo experiments with human blood, cAIMP analogs can induce the production of type I interferons (IFNs) and pro-inflammatory cytokines.
Smiles
O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@]4([C@]1(OP(=O)(O)OC[C@@]5([C@@](OP(=O)(O)OC4)([C@@H](O)[C@@H](O5)N6C7=C(N=C6)C(=O)N=CN7)[H])[H])[H])[H]
Molecular Formula
C20H23N9O13P2
Molecular Weight
659.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-134375CAIMP
tlrl-nacaidf-2cAIMP Difluor

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