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(R) -9b

CAT: 0931-T201776-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T201776-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1655527-68-6
Target
JAK, ACK1
Related Pathways
Stem Cells, Angiogenesis, Chromatin/Epigenetic, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Bioactivity
(R) -9b is an effective inhibitor of the ACK1 tyrosine kinase (IC50=56 nM) and exhibits anticancer activity. It selectively targets ACK1 but also inhibits kinases in the JAK family, specifically JAK2 and Tyk2. (R) -9b is used in research related to hormone-regulated cancers, such as prostate cancer and breast cancer.
Smiles
N(C1=CC=C(C=C1)N2CCN(C)CC2)C=3N=C(NC[C@H]4CCCO4)C(Cl)=CN3
Molecular Formula
C20H27ClN6O
Molecular Weight
402.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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