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Methacycline

CAT: 0931-T201726-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T201726-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
914-00-1
Target
CaSR, Antibiotic
Related Pathways
Microbiology/Virology, GPCR/G Protein
Bioactivity
Methacycline, a tetracycline antibiotic, inhibits bacterial protein synthesis and effectively suppresses epithelial-mesenchymal transition (EMT) . It blocks EMT in vitro and inhibits fibrogenesis in vivo without directly affecting the TGF-β1Smad signaling pathway. As an antimicrobial agent, Methacycline holds potential for research in pulmonary fibrosis.
Smiles
O[C@]12[C@]([C@H](N(C)C)C(O)=C(C(N)=O)C1=O)([C@@H](O)[C@]3(C(=C2O)C(=O)C=4C(C3=C)=CC=CC4O)[H])[H]
Molecular Formula
C22H22N2O8
Molecular Weight
442.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C