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DHICA

CAT: 0931-T201499-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T201499-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
4790-08-3
Target
Endogenous Metabolite, DUB, Arrestin, GPCR, PARP
Related Pathways
Chromatin/Epigenetic, Cell Cycle/Checkpoint, Endocrinology/Hormones, DNA Damage/DNA Repair, GPCR/G Protein, Metabolism, Ubiquitination
Bioactivity
DHICA (5,6-Dihydroxyindole-2-carboxylic acid) is an intermediate in melanin synthesis and a component of eumelanin, as well as acting as a moderate potency agonist of GPR35. In the U2OS cell line, DHICA demonstrates the ability to induce β-arrestin translocation signaling with an EC50 value of 23.2 μM. Additionally, it plays a significant role in promoting and protecting against DNA damage.
Smiles
O=C(O)C1=CC=2C=C(O)C(O)=CC2N1
Molecular Formula
C9H7NO4
Molecular Weight
193.16
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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OR1007070DHICA
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GTR18852121Mouse 5,6-dihydroxyindole-2-carboxylic acid oxidase, DHICA oxidase ELISA Kit
MBS9428879-01Mouse 5, 6-dihydroxyindole-2-carboxylic acid oxidase, DHICA oxidase ELISA Kit
134963TYRP1 (Tyrosinase-related Protein 1, TRP1, TRP-1, TRP, TYRP, TYRRP, 5,6-dihydroxyindole-2-carboxylic Acid Oxidase, DHICA Oxidase, Catalase B, CATB, CAS2, Glycoprotein 75, GP75, Melanoma Antigen gp75)
134963-APCTYRP1 (Tyrosinase-related Protein 1, TRP1, TRP-1, TRP, TYRP, TYRRP, 5,6-dihydroxyindole-2-carboxylic Acid Oxidase, DHICA Oxidase, Catalase B, CATB, CAS2, Glycoprotein 75, GP75, Melanoma Antigen gp75) (APC)
MBS6397778-01TYRP1 (Tyrosinase-related Protein 1, TRP1, TRP-1, TRP, TYRP, TYRRP, 5,6-dihydroxyindole-2-carboxylic Acid Oxidase, DHICA Oxidase, Catalase B, CATB, CAS2, Glycoprotein 75, GP75, Melanoma Antigen gp75) (Biotin)

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