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Homer

CAT: 0931-T201354-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T201354-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2737222-94-3
Target
DNA/RNA Synthesis, Others, PROTACs
Related Pathways
PROTAC, Others, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Bioactivity
Homer is a probe designed to target WD repeat domain 5 (WDR5) . In MV4-11 cells, Homer induces the degradation of WDR5 with a half-maximal degradation concentration (DC50) of 53 nM. At a concentration of 1 μM, Homer decreases the protein levels of WDR5 in MV4-11 cells without affecting the mRNA levels that encode WDR5.
Smiles
N(C(=O)C=1C(C(F)(F)F)=CC(=O)NC1)C2=C(C=CC(=C2)C3=CC=C(C(NCCCCC(N[C@H](C(=O)N4[C@H](C(NCC5=CC=C(C=C5)C=6SC=NC6C)=O)C[C@@H](O)C4)C(C)(C)C)=O)=O)C=C3)N7CCN(C)CC7
Molecular Formula
C52H60F3N9O7S
Molecular Weight
1012.15
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
GTR19239537-01Homer
70R-12718Homer antibody
H6850-05BHomer 1
H6852Homer 3 (Homer Protein Homolog 3, HOMER3, Homer-3, VESL3)
MBS6481099-01Homer 3 (Homer Protein Homolog 3, HOMER3, Homer-3, VESL3) (FITC)
MBS6481097-01Homer 3 (Homer Protein Homolog 3, HOMER3, Homer-3, VESL3) (APC)
MBS6481096-01Homer 3 (Homer Protein Homolog 3, HOMER3, Homer-3, VESL3) (AP)
247179HOMER3 (Homer Homolog 3 (Drosophila), HOMER-3)
127996HOMER3 (Homer Protein Homolog 3, Homer-3)
MBS6481106-01Homer 3 (Homer Protein Homolog 3, HOMER3, Homer-3, VESL3) (PE)

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